Open AccessCyst Fluid Biomarkers - Diagnosis and Prediction of Malignancy for Cystic Lesions of the Pancreas
Author(s) -
Aadhithya Raman,
Anne Marie Len
Publication year - 2018
Publication title -
visceral medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.598
H-Index - 17
eISSN - 2297-475X
pISSN - 2297-4725
DOI - 10.1159/000490137
Subject(s) - pancreas , cyst , malignancy , medicine , intraductal papillary mucinous neoplasm , dysplasia , pathology , adenocarcinoma , cancer
Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.