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Atypical Case of Rosai-Dorfman Disease of the Lacrimal Gland with Adjacent Bone Erosion
Author(s) -
Mohammad Dahrouj,
Frederick A. Jakobiec,
Natalie Wolkow,
Victoria Starks,
Grace Lee
Publication year - 2018
Publication title -
ocular oncology and pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.444
H-Index - 10
eISSN - 2296-4681
pISSN - 2296-4657
DOI - 10.1159/000489127
Subject(s) - medicine , rosai–dorfman disease , emperipolesis , histiocyte , pathology , sinus histiocytosis with massive lymphadenopathy , differential diagnosis , diplopia , lacrimal gland , orbit (dynamics) , optic neuropathy , etiology , cervical lymphadenopathy , dermatology , disease , anatomy , optic nerve , surgery , engineering , aerospace engineering
Rosai-Dorfman disease (RDD) is a rare, self-limited disorder of unknown etiology that affects children and young adults worldwide and typically manifests as chronic, painless cervical lymphadenopathy. Orbital involvement is very rare and may be an isolated extranodal manifestation or associated with concurrent systemic disease. Adjacent bone involvement is most exceptional, and secondary optic neuropathy has never been reported.

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