Open AccessMicroRNAs Associated with Epithelial-Mesenchymal Transition Can Be Targeted to Inhibit Peritoneal Dissemination of Human Scirrhous Gastric Cancers
Author(s) -
Yoshiyuki Takei,
Guodong Shen,
Ayami Morita-Kondo,
Toshifumi Hara,
Keichiro Mihara,
Kazuyoshi Yanagihara
Publication year - 2018
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000488801
Subject(s) - microrna , epithelial–mesenchymal transition , cancer research , homeobox , cancer , cell culture , medicine , biology , metastasis , gene , gene expression , genetics
Scirrhous gastric cancers grow rapidly, and frequently invade the peritoneum. Such peritoneal dissemination properties markedly reduce patient survival. Thus, an effective means for inhibiting peritoneal dissemination is urgently required.