Open AccessExpression and Clinical Implication of Autophagy-Associated Protein p62 in Osteosarcoma
Author(s) -
Hangzhan Ma,
Xiaoyang Li,
Jinglu Wang,
Francis J. Hornicek,
Cassandra Garbutt,
Chang Xu,
Zhenfeng Duan
Publication year - 2018
Publication title -
oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.987
H-Index - 98
eISSN - 1423-0232
pISSN - 0030-2414
DOI - 10.1159/000487437
Subject(s) - osteosarcoma , autophagy , cancer research , medicine , biology , cancer , oncology , genetics , apoptosis
Recent studies highlight the role of autophagy in cancer tumorigenesis, recurrence, metastasis, and chemoresistance. p62 is an adapter protein that is crucial for the autophagy pathway. In this study, we will describe the expression of p62 and its correlation with clinic prognosis in osteosarcoma.