Open AccessLong-Term Outcome of Adalimumab in a Young Girl with Hidradenitis Suppurativa
Author(s) -
Teresa Oranges,
Andrea Chiricozzi,
Michela Ian,
Marco Romanelli,
Valentina Dini
Publication year - 2018
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000487365
Subject(s) - hidradenitis suppurativa , medicine , adalimumab , isotretinoin , girl , young adult , surgery , pediatrics , dermatology , disease , acne , psychology , developmental psychology
Hidradenitis suppurativa (HS) is a chronic, burdensome inflammatory skin disorder mainly affecting adults with an infrequent onset during childhood or adolescence. Guidelines regarding the therapeutic drugs in pediatric HS patients are lacking. We describe the case of a 16-year-old girl affected by HS with a massive impact of the disease on her daily activities. She underwent antibiotics, estroprogestinics, isotretinoin, and drainage procedures with partial and short-term improvement. We treated the patient with adalimumab and assessed disease severity using BMI, pain VAS, Hurley, m-Sartorius, and HS-PGA. The treatment has been continued for 4 years with a strong improvement of clinical and psychological outcome. No side effects were recorded throughout the treatment period.