Open AccessCoexisting Heart Failure and Chronic Obstructive Pulmonary Disease: Report of Two Cases Treated with Indacaterol/Glycopyrronium
Author(s) -
Eugenio Roberto Cosentino,
Daniela Degli Esposti,
Rinaldo Miceli,
C. Bentivenga,
Matteo Landolfo,
Ilaria Ricci Iamino,
Luca Spinardi,
G Magrì,
Claudio Borghi
Publication year - 2018
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000487169
Subject(s) - indacaterol , medicine , copd , heart failure , concomitant , cardiology , pulmonary disease , comorbidity , asthma , bronchodilator
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide, and it is associated with a high economic burden. Heart failure shares some general symptoms with COPD; thus, diagnosing COPD is difficult in subjects with a history of heart failure, and spi-rometry is mandatory for confirmation. Moreover, COPD is a highly prevalent comorbidity negatively impacting the outcome of heart failure patients. We document here the treatment with indacaterol/glycopyrronium in 2 patients with concomitant COPD and heart failure. Overall, the combination of indacaterol and glycopyrronium resulted in a reciprocal potentiation with a maximal bronchodilatory effect.