Open AccessAssociation between COMT Polymorphism Val158Met and Opioid Consumption in Patients with Postoperative Pain: A Meta-Analysis
Author(s) -
Bo Hu,
Xiaomin Zhang,
Guangtao Xu,
Qinmei Zhang,
Ping Qian,
Shengbing Liu,
Jia Zhu,
Ruilin Shen
Publication year - 2018
Publication title -
neurosignals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.755
H-Index - 67
eISSN - 1424-8638
pISSN - 1424-862X
DOI - 10.1159/000487038
Subject(s) - meta analysis , opioid , medicine , catechol o methyl transferase , cochrane library , chronic pain , anesthesia , allele , psychiatry , gene , genetics , biology , receptor
Several factors influencing postoperative pain and the effect of opioid analgesics have been investigated on an individual level. The aim of this study was to clarify the impact of catecholamine-O-methyltransferase (COMT) gene Val158Met on opioid consumption in postoperative patients.