Open AccessAn Overview on Renoprotective Effects of Thymoquinone
Author(s) -
Hanieh Shaterzadeh-Yazdi,
Mohammad-Foad Noorbakhsh,
Saeed Samarghandian,
Tahereh Farkhondeh
Publication year - 2018
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000486829
Subject(s) - thymoquinone , nigella sativa , medicine , renal ischemia , kidney , nephrotoxicity , pharmacology , oxidative stress , diabetic nephropathy , nephropathy , inflammation , antioxidant , ischemia , diabetes mellitus , reperfusion injury , traditional medicine , endocrinology , chemistry , biochemistry
Kidneys as vital organs remove waste material from blood. Additionally, they may also have a role in the electrolyte balance, regulation of blood pressure, and red blood cell genesis. Kidney diseases may be caused by several factors such as ischemia/reperfusion injury, diabetes, and nephrotoxic agents. Oxidative stress and inflammation are involved in the pathogenesis and progression of kidney diseases. Traditionally, natural antioxidants are used for treatment of renal failure in various countries.