Open AccessSerum Levels of Interleukin-2 in Patients with Alopecia Areata: Relationship with Clinical Type and Duration of the Disease
Author(s) -
Emina Kasumagić-Halilović,
Semra Čavaljuga,
Nermina Ovčina-Kurtović,
Lamija Zečević
Publication year - 2018
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000486462
Subject(s) - alopecia areata , medicine , duration (music) , disease , interleukin , dermatology , immunology , gastroenterology , cytokine , art , literature
Alopecia areata (AA) is a disease characterized by focally, nonscarring hair loss on the scalp or any hair-bearing surface. The etiology is unknown, although the evidence suggests that AA is an immunologically mediated disease. In the pathogenesis of AA, Th1 immune response is predominant. A special cytokine profile is created by Th1 cells, which disturbs the natural balance of the cytokine networks and leads to inflammatory reaction and follicle damage.