Open AccessReproductive Hormones and Their Receptors May Affect Lung Cancer
Author(s) -
Mengmeng Dou,
Kuichun Zhu,
Zhirui Fan,
Yuxuan Zhang,
Xiufang Chen,
Xueliang Zhou,
Xianfei Ding,
Lifeng Li,
Zhenyang Gu,
Ming Guo,
Ming Yan,
Xiaoming Deng,
Ping Shen,
Shuling Wang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000485538
Subject(s) - ovariectomized rat , medicine , endocrinology , lung cancer , hormone , receptor , testosterone (patch) , androgen receptor , immunohistochemistry , biology , lung , cancer , estrogen receptor , andrology , breast cancer , prostate cancer
In contrast to men, women have experienced a rapid increase in lung cancer mortality. Numerous studies have found that the sex differences in lung cancer are due to reproductive hormones. Experiments in female mice with and without ovariectomy were performed to explore the possible mechanism by which sex hormones (and their receptors) influence lung cancer.