MiR-146a Aggravates LPS-Induced Inflammatory Injury by Targeting CXCR4 in the Articular Chondrocytes | Zendy

Taitao Sun | Zendy; Xianjun Li | Zendy; Hua Song | Zendy; Fei Gao | Zendy; Guannan Zhou | Zendy; Xiaoyan Li | Zendy; Zhentong Chen | Zendy; Lei Chen | Zendy

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MiR-146a Aggravates LPS-Induced Inflammatory Injury by Targeting CXCR4 in the Articular Chondrocytes

Author(s) -

Taitao Sun,

Xianjun Li,

Hua Song,

Fei Gao,

Guannan Zhou,

Xiaoyan Li,

Zhentong Chen,

Lei Chen

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485488

Subject(s) - cxcr4 , viability assay , pi3k/akt/mtor pathway , protein kinase b , chondrocyte , wnt signaling pathway , apoptosis , cancer research , signal transduction , medicine , microrna , inflammation , microbiology and biotechnology , immunology , chemistry , biology , chemokine , cartilage , gene , biochemistry , anatomy

Osteoarthritis (OA) as a degenerative disease is a major problem in ageing populations. To better understand the molecular mechanisms in the pathogenesis of OA, this study explored the role of microRNA (miR)-146a in the articular chondrocytes.

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