Open AccessHuaier Extract Inhibits Breast Cancer Progression Through a LncRNA-H19/MiR-675-5p Pathway
Author(s) -
Jijun Wang,
Xiaolong Wang,
Tong Chen,
Liyu Jiang,
Qifeng Yang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000485093
Subject(s) - cancer research , breast cancer , cancer , microrna , medicine , oncology , chemistry , gene , biochemistry
Increasing evidence indicates that Huaier extract has promising therapeutic effects against cancer. However, the mechanisms that underlie its anti-tumor effects remain unclear. In recent years, various studies have shown that long noncoding RNAs (lncRNAs) play a critical role in the regulation of cancer development and progression. Here, we explored the role of lncRNAs in Huaier-induced tumor suppression.