Curcumin Delays Retinal Degeneration by Regulating Microglia Activation in the Retina of rd1 Mice | Zendy

Yanhe Wang | Zendy; Zhiyuan Yin | Zendy; Lixiong Gao | Zendy; Dayu Sun | Zendy; Xisu Hu | Zendy; Langyue Xue | Zendy; Jiaman Dai | Zendy; Yuxiao Zeng | Zendy; Siyu Chen | Zendy; Boju Pan | Zendy; Min Chen | Zendy; Jing Xie | Zendy; Haiwei Xu | Zendy

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Curcumin Delays Retinal Degeneration by Regulating Microglia Activation in the Retina of rd1 Mice

Author(s) -

Yanhe Wang,

Zhiyuan Yin,

Lixiong Gao,

Dayu Sun,

Xisu Hu,

Langyue Xue,

Jiaman Dai,

Yuxiao Zeng,

Siyu Chen,

Boju Pan,

Min Chen,

Jing Xie,

Haiwei Xu

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000485085

Subject(s) - curcumin , retinitis pigmentosa , microglia , retinal degeneration , retina , neuroprotection , retinal , macular degeneration , neuroscience , medicine , biology , pharmacology , inflammation , ophthalmology

Retinitis pigmentosa (RP) is characterized by degeneration of photoreceptors, and there are currently no effective treatments for this disease. However, curcumin has shown neuroprotectant efficacy in a RP rat and swine model, and thus, may have neuroprotective effects in this disease.

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