Xia-Yu-Xue Decoction Inhibits Intestinal Epithelial Cell Apoptosis in CCl4-Induced Liver Fibrosis | Zendy

Wenting Ma | Zendy; Le Tao | Zendy; Wei Zhang | Zendy; Yinshen Zhu | Zendy; Dongying Xue | Zendy; Jie Zhang | Zendy; Cheng Liu | Zendy

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Xia-Yu-Xue Decoction Inhibits Intestinal Epithelial Cell Apoptosis in CCl4-Induced Liver Fibrosis

Author(s) -

Wenting Ma,

Le Tao,

Wei Zhang,

Yinshen Zhu,

Dongying Xue,

Jie Zhang,

Cheng Liu

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000484904

Subject(s) - ccl4 , occludin , apoptosis , tight junction , fibrosis , pathology , tunel assay , inflammation , lamina propria , proinflammatory cytokine , western blot , biology , carbon tetrachloride , immunology , medicine , chemistry , immunohistochemistry , epithelium , microbiology and biotechnology , biochemistry , organic chemistry , gene

Intestine-derived endotoxin is thought to play a role in the development of liver fibrosis. However, the pathological change in the intestine during liver fibrosis is still poorly understood. Here, we investigated the effects of Xia-yu-xue decoction (XYXD) on intestinal inflammation, apoptosis, and tight junction integrity in the carbon tetrachloride (CCl4)-induced liver fibrosis.

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