Remote Ischemia Preconditioning Attenuates Blood-Spinal Cord Barrier Breakdown in Rats Undergoing Spinal Cord Ischemia Reperfusion Injury: Associated with Activation and Upregulation of CB1 and CB2 Receptors | Zendy

Na Jing | Zendy; Bo Fang | Zendy; Zhilin Wang | Zendy; Hong Ma | Zendy

Open Access

Remote Ischemia Preconditioning Attenuates Blood-Spinal Cord Barrier Breakdown in Rats Undergoing Spinal Cord Ischemia Reperfusion Injury: Associated with Activation and Upregulation of CB1 and CB2 Receptors

Author(s) -

Na Jing,

Bo Fang,

Zhilin Wang,

Hong Ma

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000484460

Subject(s) - evans blue , medicine , downregulation and upregulation , anesthesia , ischemia , reperfusion injury , occludin , cannabinoid receptor type 2 , cannabinoid receptor , pharmacology , receptor , antagonist , chemistry , tight junction , biochemistry , gene

Remote ischemic preconditioning (RIPC) has protective effects on spinal cord ischemia reperfusion (I/R) injury, but the potential mechanisms remain unclear. In our study, the effects and underlying mechanisms of RIPC on blood-spinal cord barrier (BSCB) breakdown following I/R injury were investigated.

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