Open AccessCholecystokinin Expression in the Development of Postinfarction Heart Failure
Author(s) -
Xiaoying Dong,
Can Wang,
Jingqi Zhang,
Siyue Wang,
Hongjian Li,
Yang Ho Kang,
Shuge Tian,
Lu Fu
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000484454
Subject(s) - heart failure , cholecystokinin , medicine , myocardial infarction , ejection fraction , endocrinology , blot , natriuretic peptide , downregulation and upregulation , cardiology , brain natriuretic peptide , immunohistochemistry , receptor , biology , biochemistry , gene
Cholecystokinin (CCK) is expressed in cardiomyocytes and may also play an important role in cardiovascular regulation. Clinical studies have shown that plasma CCK levels are an independent marker of cardiovascular mortality in cardiac disease. However, whether the development of postinfarction heart failure is associated with changes in CCK expression is unknown.