Open AccessLong Non-Coding RNA-MALAT1 Mediates Retinal Ganglion Cell Apoptosis Through the PI3K/Akt Signaling Pathway in Rats with Glaucoma
Author(s) -
Haibo Li,
Qisheng You,
Lixin Xu,
Lixin Sun,
Aman Shah Abdul Majid,
Xiaobo Xia,
Dan Ji
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000484231
Subject(s) - malat1 , retinal ganglion cell , pi3k/akt/mtor pathway , biology , tunel assay , protein kinase b , immunocytochemistry , microbiology and biotechnology , retina , apoptosis , signal transduction , endocrinology , neuroscience , rna , biochemistry , long non coding rna , gene
The aim of the present study is to investigate the effect of long non-coding RNA-MALAT1 (LncRNA-MALAT1) on retinal ganglion cell (RGC) apoptosis mediated by the PI3K/Akt signaling pathway in rats with glaucoma.