Open AccessRare Occurrence of an Intraocular Choroidal Solitary Fibrous Tumor/Hemangiopericytoma
Author(s) -
Lorenzo Rinaldo,
Shangping Xu,
Scott D.Z. Eggers,
Diva R. Salomão,
John J. Chen,
Aditya Raghunathan
Publication year - 2017
Publication title -
ocular oncology and pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.444
H-Index - 10
eISSN - 2296-4681
pISSN - 2296-4657
DOI - 10.1159/000481947
Subject(s) - medicine , hemangiopericytoma , enucleation , solitary fibrous tumor , pathology , malignancy , choroid , immunohistochemistry , biology , surgery , cd34 , retina , stem cell , neuroscience , genetics
Tumors previously diagnosed as solitary fibrous tumors (SFT) and hemangiopericytomas (HPC) are characterized by the NAB2-STAT6 fusion gene, leading to nuclear STAT6 expression, and are now considered part of one SFT/HPC tumor entity by the 2016 World Health Organization Classification of Tumors of the Central Nervous System. We present the first primary choroidal SFT/HPC with the diagnosis confirmed by STAT6 expression.