In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice | Zendy

Lisbeth Harder | Zendy; Nancy Schanze | Zendy; Assel Sarsenbayeva | Zendy; Franziska Kugel | Zendy; Josef Köhrle | Zendy; Lutz Schomburg | Zendy; Jens Mittag | Zendy; Carolin S. Hoefig | Zendy

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In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice

Author(s) -

Lisbeth Harder,

Nancy Schanze,

Assel Sarsenbayeva,

Franziska Kugel,

Josef Köhrle,

Lutz Schomburg,

Jens Mittag,

Carolin S. Hoefig

Publication year - 2017

Publication title -

european thyroid journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.23

H-Index - 10

eISSN - 2235-0802

pISSN - 2235-0640

DOI - 10.1159/000481856

Subject(s) - endocrinology , medicine , in vivo , brown adipose tissue , thermoregulation , thermogenesis , adipose tissue , metabolism , hormone , heart rate , kidney , glycogen , cardiac function curve , thyroid , blood pressure , biology , heart failure , microbiology and biotechnology

Thyronamines are decarboxylated and deiodinated metabolites of thyroid hormones (THs). Of all possible thyronamine variants, only 3-iodothyronamine (3-T 1 AM) and iodine-free thyronamine (T 0 AM) have been detected in vivo. While intensive research has been done on the (patho-)physiological action of 3-T 1 AM, the role of T 0 AM has been studied less intensively.

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