Salvianolic Acid B Ameliorates Cognitive Deficits Through IGF-1/Akt Pathway in Rats with Vascular Dementia | Zendy

Xiaowei Ma | Zendy; Weiwei Xu | Zendy; Zhongxia Zhang | Zendy; Na Liu | Zendy; Jie Yang | Zendy; Mingwei Wang | Zendy; Yanyong Wang | Zendy

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Salvianolic Acid B Ameliorates Cognitive Deficits Through IGF-1/Akt Pathway in Rats with Vascular Dementia

Author(s) -

Xiaowei Ma,

Weiwei Xu,

Zhongxia Zhang,

Na Liu,

Jie Yang,

Mingwei Wang,

Yanyong Wang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000481849

Subject(s) - vascular dementia , dementia , protein kinase b , medicine , cognition , cognitive decline , signal transduction , endocrinology , neuroscience , psychology , biology , microbiology and biotechnology , disease

BackgroundAims: Salvianolic acid B (SalB) is a natural polyphenolic compound enriched in Salvia miltiorrhiza Bunge. Our study was designed to explore the role of Sal B on cognitive impairment in vascular dementia (VD) model rats, as well as its possible molecular mechanisms.

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