Protective Effects of Microrna-22 Against Endothelial Cell Injury by Targeting NLRP3 Through Suppression of the Inflammasome Signaling Pathway in a Rat Model of Coronary Heart Disease | Zendy

Weiqiang Huang | Zendy; Peng Wei | Zendy; RiQi Lin | Zendy; Feng Huang | Zendy

Open Access

Protective Effects of Microrna-22 Against Endothelial Cell Injury by Targeting NLRP3 Through Suppression of the Inflammasome Signaling Pathway in a Rat Model of Coronary Heart Disease

Author(s) -

Weiqiang Huang,

Peng Wei,

RiQi Lin,

Feng Huang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000481846

Subject(s) - apoptosis , inflammasome , microrna , caspase 1 , blot , microbiology and biotechnology , endothelial stem cell , cell , western blot , signal transduction , medicine , chemistry , cancer research , biology , inflammation , immunology , in vitro , biochemistry , gene

This study aimed to identify the role of microRNA-22 (miR-22) in endothelial cell (EC) injury in coronary heart disease (CHD) by targeting NLRP3 through the inflammasome signaling pathway.

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