Iodine Promotes Tumorigenesis of Thyroid Cancer by Suppressing Mir-422a and Up-Regulating MAPK1 | Zendy

Junyi Wang | Zendy; Haiou Yang | Zendy; Yiran Si | Zendy; Dongzhi Hu | Zendy; Yang Yu | Zendy; Yan Zhang | Zendy; Ming Gao | Zendy; Haiyang Zhang | Zendy

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Iodine Promotes Tumorigenesis of Thyroid Cancer by Suppressing Mir-422a and Up-Regulating MAPK1

Author(s) -

Junyi Wang,

Haiou Yang,

Yiran Si,

Dongzhi Hu,

Yang Yu,

Yan Zhang,

Ming Gao,

Haiyang Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000481844

Subject(s) - carcinogenesis , microrna , thyroid cancer , cancer research , thyroid carcinoma , thyroid , cell growth , cancer , medicine , biology , biochemistry , gene

Iodine may trigger tumorigenesis and development of thyroid carcinoma, but the mechanisms involved remained elusive. MicroRNA (MiRNAs) are known to be involved in each stage of cancer development; however, the role of miRNAs in iodine-induced tumorigenesis of thyroid carcinoma remained unknown. In this study, we aimed at investigating miRNA related signaling pathway in thyroid cancer cells.

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