Open AccessInhibition of MicroRNA-21-5p Promotes the Radiation Sensitivity of Non-Small Cell Lung Cancer Through HMSH2
Author(s) -
Shizhu Yu,
Yun Zuo,
Xiaolan Qian,
Zhipeng Chen,
Shaokai Wang,
Lei Song,
Liping Peng
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000481839
Subject(s) - transfection , flow cytometry , apoptosis , microrna , a549 cell , blot , lung cancer , microbiology and biotechnology , viability assay , mtt assay , radiation sensitivity , cell , cancer research , cell growth , cell culture , biology , chemistry , pathology , medicine , irradiation , gene , biochemistry , genetics , physics , nuclear physics
This study aimed to explore the effects of microRNA-21-5p (miR-21-5p) on the radiation sensitivity of non-small cell lung cancer (NSCLC) and the involvement of human MutS homolog 2 (hMSH2) One hundred fourteen NSCLC patients at stage II or III who received surgery and postoperative radiotherapy were enrolled in this study.