Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice | Zendy

Mingjun Xiang | Zendy; Yuting Jiang | Zendy; Zhiying Hu | Zendy; Yang Yang | Zendy; Benson O. A. Botchway | Zendy; Marong Fang | Zendy

Open Access

Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice

Author(s) -

Mingjun Xiang,

Yuting Jiang,

Zhiying Hu,

Yang Yang,

Benson O. A. Botchway,

Marong Fang

Publication year - 2017

Publication title -

neurosignals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.755

H-Index - 67

eISSN - 1424-8638

pISSN - 1424-862X

DOI - 10.1159/000481791

Subject(s) - anxiety , open field , 5 ht receptor , stimulation , psychology , serotonin , receptor , elevated plus maze , mapk/erk pathway , neuroscience , 5 ht2a receptor , medicine , endocrinology , signal transduction , biology , microbiology and biotechnology , psychiatry

Serotonin 5HT2A and 5HT1A receptors (5HT2AR, 5HT1AR) have the closest connection to anxiety-like behavior in post-traumatic stress disorder (PTSD). However, the underlying mechanism remains unclear. In this study, we explored the connection between 5HT2A and 5HT1A receptors and anxiety-like behavior.

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