Open AccessA Human Long Non-Coding RNA ALT1 Controls the Cell Cycle of Vascular Endothelial Cells Via ACE2 and Cyclin D1 Pathway
Author(s) -
Wen Li,
Rui Wang,
Jieyi Ma,
Mian Wang,
Jin Cui,
Weibin Wu,
Rui-Ming Liu,
Chunxiang Zhang,
Shenming Wang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000481756
Subject(s) - cyclin d1 , umbilical vein , cell cycle , cell growth , rna , biology , long non coding rna , small interfering rna , microbiology and biotechnology , chemistry , cell , gene , biochemistry , in vitro
ALT1 is a novel long non-coding RNA derived from the alternatively spliced transcript of the deleted in lymphocytic leukemia 2 (DLEU2). To date, ALT1 biological roles in human vascular endothelial cells have not been reported.