Open AccessKrüppel-Like Factor 7 is a Marker of Aggressive Gastric Cancer and Poor Prognosis
Author(s) -
Zhonghua Jiang,
Tingting Yu,
Zhining Fan,
Hongmei Yang,
Xin Lin
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000481748
Subject(s) - gene knockdown , lymphovascular invasion , transcription factor , cancer research , biology , cancer , oncology , medicine , gene , metastasis , genetics
Krüppel-like factor (KLF) 7 protein is a member of the KLF transcription factor family, which plays important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation and metabolism. However, the role of KLF7 in gastric cancer (GC) is unknown. The aim of this study is to explore the role of KLF7 in GC and its correlation with clinicopathological characteristics and prognosis of GC patients.