Open AccessMicroRNAs in Renal Diseases: A Potential Novel Therapeutic Target
Author(s) -
Federica Petrillo,
Anna Iervolino,
Miriam Zacchia,
Adelina Simeoni,
Cristina Masella,
Giovanna Capolongo,
Alessandra F. Perna,
Giovambattista Capasso,
Francesco Trepiccione
Publication year - 2017
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000481730
Subject(s) - microrna , biology , cancer research , pathogenesis , diabetic nephropathy , kidney , fibrosis , bioinformatics , gene , medicine , immunology , genetics
MicroRNAs (miRNAs) are a family of short noncoding RNAs that play important roles in posttranscriptional gene regulation. miRNAs inhibit target gene expression by blocking protein translation or by inducing mRNA degradation and therefore have the potential to modulate physiological and pathological processes.