Open AccessAssociation of p53 Codon 72 Polymorphism with Breast Cancer in a Rwandese Population
Author(s) -
Thierry Habyarimana,
Mohammed Attaleb,
Pacifique Mugenzi,
Jean Baptiste Mazarati,
Youssef Bakri,
Mohammed El Mzibri
Publication year - 2017
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000481664
Subject(s) - breast cancer , genotype , allele , biology , medicine , population , genetics , oncology , cancer , gene , environmental health
A common polymorphism in the tumor suppressor gene p53 at codon 72 has been suggested to play a role in the development of a number of cancers. This polymorphism has been studied in many populations worldwide, with conflicting results. The present study was planned to assess the association of p53 codon 72 polymorphism with breast cancer development in a Rwandese population.