Open AccessA 53-Year-Old Male with Relapsed Diffuse Large B-Cell Lymphoma on Chemotherapy with a New Leg Lesion
Author(s) -
Connie R. Shi,
Sarah N. Robinson,
Avery LaChance,
Martín C. Mihm,
Daniela Kroshinsky
Publication year - 2017
Publication title -
dermatopathology
Language(s) - English
Resource type - Journals
ISSN - 2296-3529
DOI - 10.1159/000481307
Subject(s) - medicine , malignancy , lymphoma , context (archaeology) , biopsy , chemotherapy , lesion , diffuse large b cell lymphoma , differential diagnosis , skin biopsy , radiology , pathology , surgery , paleontology , biology
Patients with underlying malignancy who develop new skin findings while acutely ill often require skin biopsy for histologic evaluation and/or culture to reach a diagnosis. Here, we present the case of a 53-year-old male with relapsed diffuse large B-cell lymphoma on chemotherapy who developed new skin lesions on the leg. On exam, there were 2 nickel-sized, erythematous to violaceous round plaques with central necrotic cores on the right lower leg with relatively nonspecific clinical features for which the initial differential diagnosis was broad. Consensus on a diagnosis was reached upon histologic evaluation of his skin biopsy in the context of his clinical setting. This diagnosis led to a change in treatment plan, with subsequent clinical improvement.