Open AccessPrimary Hepatic Adenosquamous Carcinoma Associated with Primary Sclerosing Cholangitis
Author(s) -
Kentaro Yamao,
Mamoru Takenaka,
Hisao Imai,
Asami Nakai,
Shunske Omoto,
Ken Kamata,
Kosuke Minaga,
Takeshi Miyata,
Toshiharu Sakurai,
Tomohiro Watanabe,
Naoshi Nishida,
Ippei Matsumoto,
Yosihumi Takeyama,
Takaaki Chikugo,
Masatoshi Kudo
Publication year - 2017
Publication title -
oncology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.987
H-Index - 98
eISSN - 1423-0232
pISSN - 0030-2414
DOI - 10.1159/000481236
Subject(s) - medicine , primary sclerosing cholangitis , adenocarcinoma , adenosquamous carcinoma , intrahepatic cholangiocarcinoma , pathology , biopsy , magnetic resonance imaging , carcinoma , radiology , cancer , disease
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disorder characterized by multiple fibrotic strictures of the bile duct. More than 40% of deaths in PSC patients are related to malignant tumors, including cholangiocarcinoma. Primary hepatic adenosquamous carcinoma (ASC) is a rare subtype of cholangiocarcinoma containing adenocarcinoma (AC) and squamous cell carcinoma (SCC) components, with a poorer prognosis than other cholangiocarcinomas. We report the first case of a hepatic ASC in a patient with PSC.