Open AccessChronic Pancreatitis Finding by Endoscopic Ultrasonography in the Pancreatic Parenchyma of Intraductal Papillary Mucinous Neoplasms Is Associated with Invasive Intraductal Papillary Mucinous Carcinoma
Author(s) -
Mamoru Takenaka,
Atsuhiro Masuda,
Hideyuki Shiomi,
Yosuke Yagi,
Yoh Zen,
Arata Sakai,
Takashi Kobayashi,
Yoshifumi Arisaka,
Yoshihiro Okabe,
Hiromu Kutsumi,
Hirochika Toyama,
Takumi Fukumoto,
Yonson Ku,
Masatoshi Kudo,
Takeshi Azuma
Publication year - 2017
Publication title -
oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.987
H-Index - 98
eISSN - 1423-0232
pISSN - 0030-2414
DOI - 10.1159/000481232
Subject(s) - medicine , intraductal papillary mucinous neoplasm , gastroenterology , pancreatitis , pancreatic cancer , pancreas , endoscopic ultrasound , pancreatic intraepithelial neoplasia , mucinous carcinoma , pathology , adenocarcinoma , cancer , radiology , pancreatic ductal adenocarcinoma
The recent guideline for intraductal papillary mucinous neoplasms (IPMNs) focuses on morphological features of the lesion as signs of malignant transformation, but ignores the background pancreatic parenchyma, including features of chronic pancreatitis (CP), which is a risk factor for pancreatic malignancies. Endoscopic ultrasonography frequently reveals evidence of CP (EUS-CP findings) in the background pancreatic parenchyma of patients with IPMNs. Therefore, we investigated whether background EUS-CP findings were associated with malignant IPMN.