Open AccessThe Protective Effects of Sika Deer Antler Protein on Cisplatin-Induced Nephrotoxicity
Author(s) -
Haiyan Yang,
Wei Li,
Lulu Wang,
Wenqing Li,
Hang Sun,
Xingxing He,
Jing Zhang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000480418
Subject(s) - antler , nephrotoxicity , cisplatin , toxicity , biology , pharmacology , medicine , ecology , chemotherapy
This study measured the effect of Sika deer (Cervus nippon Temminck) antler protein (SDAPR), glycoproteins (SDAG), and polysaccharides (SDAPO) on cisplatin-induced cytotoxicity in HEK 293 cells, and investigated the effect of SDAPR against cisplatin-induced nephrotoxicity in mice.