Open AccessA Comparative Proteomic Analysis of Erinacine A’s Inhibition of Gastric Cancer Cell Viability and Invasiveness
Author(s) -
HsingChun Kuo,
Yur-Ren Kuo,
Kam-Fai Lee,
MengChe Hsieh,
Cheng-Yi Huang,
YungYu Hsieh,
KoChao Lee,
Hsiang-Lan Kuo,
Li-Ya Lee,
Wanping Chen,
ChinChu Chen,
ShuiYi Tung
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000480338
Subject(s) - propidium iodide , protein kinase b , viability assay , apoptosis , biology , annexin , signal transduction , cell growth , microbiology and biotechnology , cancer research , cancer cell , pi3k/akt/mtor pathway , fas ligand , programmed cell death , chemistry , cancer , biochemistry , genetics
Background / Aims: Erinacine A, isolated from the ethanol extract of the Hericium erinaceus mycelium, has been demonstrated as a new alternative anticancer medicine. Drawing upon current research, this study presents an investigation of the molecular mechanism of erinacine A inhibition associated with gastric cancer cell growth.