Open AccessKnockdown of Lncrna PVT1 Enhances Radiosensitivity in Non-Small Cell Lung Cancer by Sponging Mir-195
Author(s) -
Dapeng Wu,
Yong Li,
Huixiang Zhang,
Xiaoyi Hu
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000480209
Subject(s) - pvt1 , radiosensitivity , gene knockdown , cancer research , flow cytometry , apoptosis , biology , mtt assay , in vivo , chemistry , microbiology and biotechnology , downregulation and upregulation , medicine , long non coding rna , radiation therapy , gene , biochemistry
Plasmacytoma variant translocation 1 (PVT1) exerts an oncogenic role in many tumors, including lung cancer. However, the roles of PVT1 in regulating radiosensitivity of NSCLC and its underlying mechanism are still unclear.