Open AccessTRPA1 Function in Skeletal Muscle Sensory Neurons Following Femoral Artery Occlusion
Author(s) -
Jihong Xing,
Jianhua Li
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000480003
Subject(s) - dorsal root ganglion , trpv1 , agonist , stimulation , medicine , femoral artery , transient receptor potential channel , sensory system , hindlimb , neuroscience , anatomy , chemistry , anesthesia , receptor , dorsum , biology
Transient receptor potential channel A1 (TRPA1) is engaged in amplified autonomic responses evoked by stimulation of muscle afferent nerves in rats with experimental peripheral arterial disease. The purposes of this study were to characterize current responses induced by activation of TRPA1 in dorsal root ganglion (DRG) neurons of control limbs and limbs with femoral artery occlusion.