Infusion of Valproic Acid Into the Renal Medulla Activates Stem Cell Population and Attenuates Salt-Sensitive Hypertension in Dahl S Rats | Zendy

Zhengchao Wang | Zendy; Qing Zhu | Zendy; Weili Wang | Zendy; Fan Yi | Zendy; PinLan Li | Zendy; Krishna M. Boini | Zendy; Ningjun Li | Zendy

Open Access

Infusion of Valproic Acid Into the Renal Medulla Activates Stem Cell Population and Attenuates Salt-Sensitive Hypertension in Dahl S Rats

Author(s) -

Zhengchao Wang,

Qing Zhu,

Weili Wang,

Fan Yi,

PinLan Li,

Krishna M. Boini,

Ningjun Li

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000478955

Subject(s) - valproic acid , renal medulla , endocrinology , stem cell , population , medicine , pharmacology , kidney , chemistry , microbiology and biotechnology , biology , neuroscience , environmental health , epilepsy

Our previous study has detected a stem cell deficiency in the renal medulla in Dahl salt-sensitive (S) rats. This study determined whether infusion of valproic acid (VA), an agent known to stimulate the stem cell function, attenuated salt-sensitive hypertension in Dahl S rats.

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