Open AccessInhibition of the lncRNA Mirt1 Attenuates Acute Myocardial Infarction by Suppressing NF-κB Activation
Author(s) -
Xiangrao Li,
Jian Zhou,
Kai Huang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000478870
Subject(s) - gene knockdown , apoptosis , myocardial infarction , downregulation and upregulation , hypoxia (environmental) , inflammation , in vivo , nf κb , cancer research , microbiology and biotechnology , in vitro , myocyte , signal transduction , chemistry , medicine , biology , biochemistry , gene , organic chemistry , oxygen
The expression of a novel lncRNA, myocardial infarction associated transcript 1(Mirt1), has been shown to be upregulated in acute myocardial infarction (AMI). However, the role of Mirt1 in AMI is not clear.