Open AccessEffect of TNF-α Inhibition on Bone Marrow-Derived Mesenchymal Stem Cells in Neurological Function Recovery after Spinal Cord Injury via the Wnt Signaling Pathway in a Rat Model
Author(s) -
Renjun Peng,
Jiang Bo,
Xiaoyi Ding,
He Huang,
Yi-Wei Liao,
Gang Peng,
Quan Cheng,
Jian Xi
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000477891
Subject(s) - wnt3a , tumor necrosis factor alpha , wnt signaling pathway , mesenchymal stem cell , spinal cord injury , neural stem cell , medicine , blot , stem cell , spinal cord , pathology , endocrinology , biology , signal transduction , microbiology and biotechnology , psychiatry , biochemistry , gene
The present study aimed to examine the effect of tumor necrosis factor-α (TNF-α) inhibition on bone marrow-derived mesenchymal stem cells (BMSCs) in neurological function recovery after spinal cord injury (SCI) via the Wnt signaling pathway in a rat model.