Open AccessThe “Burden” of Malignancy in a Tertiary Hospital Intensive Cardiovascular Care Unit
Author(s) -
Israel Mazin,
Shlomi Matetzky,
Linor Shemer,
Dana Fourey,
Paul Fefer,
Amit Segev,
Arsalan AbuMuch,
Roy Beigel,
Elad Asher
Publication year - 2017
Publication title -
cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 63
eISSN - 1421-9751
pISSN - 0008-6312
DOI - 10.1159/000477840
Subject(s) - medicine , malignancy , intensive care unit , incidence (geometry) , mortality rate , observational study , myocardial infarction , logistic regression , pediatrics , optics , physics
Objectives: During the past decade, the most common causes of mortality and morbidity were cardiovascular diseases and malignancies. The aim of the current study was to describe the incidence, course of admission, and short-term (30-day) prognosis of patients with and without malignancy, admitted to a tertiary center intensive cardiovascular care unit (ICCU). Methods: A prospective observational study of 2,259 patients admitted to the ICCU was conducted between January 2014 and December 2015. Patients with malignancies (n = 256) were divided into 2 groups: those with solid and those with homogenous tumors. Results: The time of diagnosis was categorized into 3 patient groups: recent ( 24 months), 148 patients (58%). Those with a history of malignancy were older (73 ± 12 vs. 64 ± 15, p < 0.001) and were more likely to be female (p = 0.002). After using a multivariate logistic regression model analysis, no differences were found in therapeutic interventions and clinical outcomes, including major bleeding and acute renal failure, between patients with and without malignancies. Conclusions: Patients with a malignancy comprised about 10% of the entire ICCU population. While mortality was independently associated with advanced age, renal failure, and a diagnosis of ST-elevation myocardial infarction, malignancy alone was not found to be independently associated with a higher mortality rate at 30 days of follow-up.