Open AccessPTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor κB Pathway
Author(s) -
Caihong Liang,
X Wang,
Jianping Hu,
Xiaoqing Lian,
Tiantian Zhu,
Zhang Hui,
Ning Gu,
Jun Li
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000477596
Subject(s) - cd36 , oxidative stress , apoptosis , oil red o , reactive oxygen species , biology , tlr4 , superoxide dismutase , microbiology and biotechnology , signal transduction , biochemistry , chemistry , receptor , in vitro , adipogenesis
Critical roles of phosphatase receptor type O (PTPRO) and toll-like receptor 4 (TLR4) have been implicated in inflammation. However, little is known about their functional effects on atherosclerosis (AS). We aim to study their potential function in AS.