MicroRNA-181a-5p Impedes IL-17-Induced Nonsmall Cell Lung Cancer Proliferation and Migration through Targeting VCAM-1 | Zendy

Yang Cao | Zendy; Dan Zhao | Zendy; Ping Li | Zendy; Lanrong Wang | Zendy; Bingli Qiao | Zendy; Xiaoyan Qin | Zendy; Lei Li | Zendy; Yang Wang | Zendy

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MicroRNA-181a-5p Impedes IL-17-Induced Nonsmall Cell Lung Cancer Proliferation and Migration through Targeting VCAM-1

Author(s) -

Yang Cao,

Dan Zhao,

Ping Li,

Lanrong Wang,

Bingli Qiao,

Xiaoyan Qin,

Lei Li,

Yang Wang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000477389

Subject(s) - microrna , cancer research , vcam 1 , cell growth , downregulation and upregulation , transfection , biology , cell adhesion , metastasis , lung cancer , cell culture , cell , stat3 , cancer , medicine , microbiology and biotechnology , signal transduction , biochemistry , genetics , gene

The contribution of the inflammatory mediator interleukin-17 (IL-17) in nonsmall cell lung cancer (NSCLC) malignancy has been reported in the literature. MicroRNA-181a-5p (miR-181a-5p) acts as a tumor suppressor which can regulate target gene at the posttranscriptional level. Our study aimed to investigate the interaction between IL-17 and miR-181a-5p in NSCLC.

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