Open AccessMicronutrients, Essential Fatty Acids and Bone Health in Phenylketonuria
Author(s) -
Serwet Demirdas,
Francjan J. van Spronsen,
Carla E. M. Hollak,
Hanneke J. H. van der Lee,
Peter H. Bisschop,
Frédéric M. Vaz,
Nienke M. ter Horst,
M. Estela Rubio-Gozalbo,
Annet M. Bosch
Publication year - 2017
Publication title -
annals of nutrition and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.926
H-Index - 81
eISSN - 1421-9697
pISSN - 0250-6807
DOI - 10.1159/000465529
Subject(s) - micronutrient , medicine , endocrinology , bone mineral , population , polyunsaturated fatty acid , vitamin d and neurology , osteoporosis , fatty acid , chemistry , biochemistry , environmental health , pathology
In phenylketonuria (PKU), a natural protein-restricted dietary treatment prevents severe cognitive impairment. Nutrient deficiencies may occur due to strict diet. This study is aimed at evaluating the dietary intake and blood concentrations of micronutrients and essential fatty acids (FA), bone mineral density (BMD) and fracture history in patients on long-term dietary treatment.