Open AccessWater-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon
Author(s) -
Abderrahim Nemmar,
Suhail Al-Salam,
Sumaya Beegam,
Priya Yuvaraju,
Abderrahim Oulhaj,
Badreldin H. Ali
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000464117
Subject(s) - betaine , circulatory system , smoke , chemistry , microbiology and biotechnology , biology , medicine , biochemistry , organic chemistry
It has been shown, both experimentally and clinically, that water-pipe smoke (WPS) exposure adversely affects the cardiovascular system (CVS) through the generation of oxidative stress and inflammation. Betaine, a naturally occurring compound in common foods, has antioxidant and anti-inflammatory actions. However, its potential to mitigate the adverse effect of WPS on the CVS has never been reported before. This is the subject of this study in mice.