A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells | Zendy

Xi Han | Zendy; Shuai Zhen | Zendy; Zhongxue Ye | Zendy; Jiaojiao Lu | Zendy; Lijie Wang | Zendy; Pan Li | Zendy; Jie Li | Zendy; Xia Zheng | Zendy; Huijin Li | Zendy; Wei Chen | Zendy; Le Zhao | Zendy; Xu Li | Zendy

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A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells

Author(s) -

Xi Han,

Shuai Zhen,

Zhongxue Ye,

Jiaojiao Lu,

Lijie Wang,

Pan Li,

Jie Li,

Xia Zheng,

Huijin Li,

Wei Chen,

Le Zhao,

Xu Li

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000460618

Subject(s) - cisplatin , ectopic expression , ovarian cancer , dnmt1 , microrna , cancer research , methylation , downregulation and upregulation , flow cytometry , chemistry , apoptosis , microbiology and biotechnology , dna methylation , dna methyltransferase , cell culture , cancer , biology , methyltransferase , gene expression , chemotherapy , gene , genetics , biochemistry

Many microRNAs (miRs) are dysregulated in cancers, and aberrant miR expression patterns have been suggested to correlate with chemo-resistance of cancer cells. We aim to study the role of miR-30 family members in cisplatin-resistance of ovarian cancer cells.

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