Open AccessChrysotile Causes Human Bronchial Epithelial Cell Apoptosis in Response to the Fas-Mediated Apoptosis Pathway
Author(s) -
Min Zhang,
Junqiang Chen,
Zhaoqiang Jiang,
Lijin Zhu,
Wei Wu,
Yun Xiao,
Kun Chen
Publication year - 2017
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000455902
Subject(s) - apoptosis , chrysotile , caspase 8 , fas receptor , microbiology and biotechnology , fas ligand , western blot , chemistry , programmed cell death , biology , caspase 3 , biochemistry , gene , asbestos , materials science , metallurgy
Asbestos is harmful to human health. However, the pathogenicity of chrysotile is a controversial matter. This study aimed to investigate the apoptosis of a human bronchial epithelial cell line (BEAS-2B) exposed to chrysotile that may function in part through the Fas death receptor pathway.