PHLDA1 Promotes Lung Contusion by Regulating the Toll-Like Receptor 2 Signaling Pathway | Zendy

Shaohua Wang | Zendy; Hua Zhang | Zendy; An Wang | Zendy; Dayu Huang | Zendy; Jie Fan | Zendy; Lu Lu | Zendy; Xiaofeng Chen | Zendy

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PHLDA1 Promotes Lung Contusion by Regulating the Toll-Like Receptor 2 Signaling Pathway

Author(s) -

Shaohua Wang,

Hua Zhang,

An Wang,

Dayu Huang,

Jie Fan,

Lu Lu,

Xiaofeng Chen

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453173

Subject(s) - tlr2 , lung , tumor necrosis factor alpha , receptor , proinflammatory cytokine , inflammation , signal transduction , apoptosis , cancer research , medicine , chemokine , oncogene , immunology , pathology , biology , tlr4 , microbiology and biotechnology , cell cycle , biochemistry

Lung contusion is a potentially lethal injury. Pleckstrin homology-like domain family A, member-1 (PHLDA1) is known to play crucial roles in cell proliferation and apoptosis. In this study, we investigated the biological role of PHLDA1 in lung contusion.

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