Open AccessDietary Genistein Rescues Reduced Basal Chloride Secretion in Diabetic Jejunum via Sex-Dependent Mechanisms
Author(s) -
Shawn Catmull,
Faisal Masood,
Sydney Schacht,
Robert Dolan,
Daniel Stegman,
Lana Leung,
Layla AlNakkash
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000452549
Subject(s) - genistein , endocrinology , medicine , basal (medicine) , jejunum , biology , western blot , chemistry , diabetes mellitus , biochemistry , gene
The goal of this study was to determine the effect of dietary genistein (naturally occurring phytoestrogen) on jejunal secretory function in a clinically relevant model of diabetes and obesity, the leptin-defIcient ob/ob mouse.