Open AccessSensitive Skin: Assessment of the Skin Barrier Using Confocal Raman Microspectroscopy
Author(s) -
R.J.H. Richters,
Denise Falcone,
N. Uzunbajakava,
Babu Varghese,
Peter Caspers,
Gerwin J. Puppels,
P.E.J. van Erp,
Peter C M van de Kerkhof
Publication year - 2017
Publication title -
skin pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 74
eISSN - 1660-5535
pISSN - 1660-5527
DOI - 10.1159/000452152
Subject(s) - transepidermal water loss , stratum corneum , chemistry , medicine , endocrinology , pathology
Sensitive skin (SS), a frequently reported condition in the Western world, has been suggested to be underlined by an impaired skin barrier. The aim of this study was to investigate the skin barrier molecular composition in SS subjects using confocal Raman microspectroscopy (CRS), and to compare it with that of non-SS (NSS) individuals as well as atopic dermatitis (AD) and allergic rhinoconjunctivitis (AR) subjects, who frequently report SS.