Open AccessThe Three Sisters of Fate in Multiple Sclerosis: Klotho (Clotho), Fibroblast Growth Factor-23 (Lachesis), and Vitamin D (Atropos)
Author(s) -
Hamit Yaşar Elli̇dağ,
Necat Yılmaz,
Fatma Kurtuluş,
Özgür Aydın,
Esin Eren,
Ayça İnci,
Süleyman Dolu,
Fatma Demet Arslan Ince,
Özlem Giray,
Ayli̇n Yaman
Publication year - 2016
Publication title -
annals of neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.545
H-Index - 19
eISSN - 0976-3260
pISSN - 0972-7531
DOI - 10.1159/000449181
Subject(s) - vitamin d and neurology , klotho , multiple sclerosis , medicine , fibroblast growth factor 23 , fibroblast growth factor , endocrinology , fibroblast , gastroenterology , calcium , immunology , biology , parathyroid hormone , biochemistry , receptor , in vitro , kidney
The klotho (Klt)-fibroblast growth factor-23 (FGF-23)-vitamin D axis is the main component of calcium (Ca) and phosphorus (P) metabolisms; on the contrary, it is also secreted from the choroid plexus (CP).