Open AccessAntiangiogenic Therapy Induces Hepatic Tumor Vascular Network Rearrangement to Receive Perfusion via the Portal Vein and Hepatic Artery
Author(s) -
Wonseok Kang,
Joon Seok Lim,
MiSuk Park,
Gou Young Koh,
Honsoul Kim
Publication year - 2016
Publication title -
journal of vascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 74
eISSN - 1423-0135
pISSN - 1018-1172
DOI - 10.1159/000448734
Subject(s) - medicine , perfusion , artery , portal vein , vein , cardiology , hepatic portal vein , right gastric vein , portal venous pressure , portal hypertension , cirrhosis
Hepatic malignancies can easily develop resistance to antiangiogenic therapy, but the underlying mechanism remains poorly understood. This study explores whether antiangiogenic therapy influences the tumor vascular network and/or the vessels feeding the hepatic tumor.